Dundee is one of the most exciting and dynamic biomedical and life sciences communities in the UK. This small city is home to the University of Dundee, one of the leading universities in Europe for research in life science, and our neighbours are a unique mix of international academics and leading life sciences companies revolutionising the way the world views this small northeast corner of Scotland.
The patented technology underpinning Cypex’s products was developed at the University of Dundee during a five-year project in partnership with a number of leading international pharmaceutical companies. The technology enables the expression of human drug-metabolising enzymes in bacteria, without the need for large modifications to be made to the proteins.
Since the release of our first recombinant cytochrome P450 (CYP) in early 2000, we have rapidly expanded our portfolio to more than 100 products covering human drug-metabolising enzymes (including CYPs, SULTs, UGTs, CES and AOX), mouse, rat, monkey, pig and dog CYPs, fine chemicals for use as substrates, metabolite standards and inhibitors, and a range of antibodies. We have also obtained the prestigious ISO 9001 quality accreditation.
Drawing on our expertise in expressing recombinant cytochrome P450s (CYP) and in drug metabolism, we also offer a bespoke service for custom protein expression and the production of drug metabolites.
To complement our high-quality products, we have maintained close links with the University of Dundee and the industrial members of the consortium involved in the original project. This enables Cypex to remain at the forefront of in vitro drug metabolism technology.
We work with international pharmaceutical companies and world-leading academics to provide relevant tools to give reliable early insight during initial stage drug development and research studies. Here’s what they have to say about working with us.