The following pages give details of protocols for determining
cytochrome P450 activity using a fluorescence plate reader. The optimal
incubation conditions can also be used to investigate CYP inhibition in
a high-throughput format.
(MFC) (updated 13th March 2008)
(7BQ) (updated 20th March 2008)
instrument used at Cypex is a Tecan Infinite M-200 equipped with
non-plate reader QC assays used at Cypex can be found on this page.
under licence from BTG International Ltd (AU730155, EP0914446,
US6566108 and other patents pending).
United States Patent Nos. 5,420,027 or 5,240,831, Canada Patent No.
2100245 and other patents pending.