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Company News, New Products, Meetings where Cypex is Exhibiting


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Company News

20th June 2013
Cypex reaffirms its commitment to support and promote the understanding of xenobiosis by continuing to support the International Society for the Study of Xenobiotics (ISSX) at the highest, Global Partner, level for the sixth consecutive year.

3rd - 4th June 2013
Cypex hosts a Drug Metabolism Discussion Group (DMDG) meeting on non-CYP-mediated metabolism.

29th August 2011
A further three enzymes (CYPs 2B6, 2C8 and 3A5) are added to the panel of human CYPs available in Cypex's CYP inhibition screening service using fluorescent end-points.

December 2010
An article on Cypex is published in Enterprising Scotland magazine.

5th October 2010
Following the appointment of Dr Caroline Peet earlier this year Cypex has launched its CYP inhibition screening services.

31st March 2010
RILD and LabPartner are appointed distributors for Cypex products in China.

27th May 2009
Green enzymes! The WES 18/80 turbine is now operational, providing electricity for the manufacture of Bactosomes.  The turbine is predicted to provide much more power than is used by Cypex making the company a net exporter of green energy.

WES 18/80 turbine

27th February 2009
Cypex demonstrates its commitment to support the advancement of understanding xenobiotic metabolism by supporting the International Society for the Study of Xenobiotics (ISSX) at the highest, Major Donor, level for the second year running.

9th February 2009
Cypex awarded a joint grant with Prof Andrew Munro, University of Manchester for a CASE studentship entitled Evolution of efficient P450 biocatalysts for human drug metabolite generation.

20th August 2008
Cypex is granted planning permission for the erection of an 80 kW wind turbine. The turbine should provide up to twice the power consumed by Cypex.

17th June 2007
Cypex appoints Krishgen Biosystems as a distributor for the Indian market.

2nd November 2006
Cypex appoints Precision Technologies as a distributor for Singapore, Malaysia, Indonesia and Thailand.

17th April 2006
Cypex starts operating from new premises in Dundee Medipark.

10th October 2005
Building work starts on Cypex's new headquarters and laboratory in Dundee Medipark.

10th January 2005
Cypex announces plans to build new headquarters and laboratory in prestigious Medipark in Dundee. Planning permission has been granted for a building that is three times the size of Cypex's current premises.

10th December 2004
Cypex appoints AiBST as a distributor for the African market.

1st July 2004
Cypex appoints Jingmei Biotech Co. Ltd. as a distributor for its products in China and MGP Co. Ltd as a distributor in the Czech Republic.

6th October 2003
Cypex and BioDynamics Research Ltd, Rushden, UK sign joint manufacturing / distribution agreement. Cypex will distribute fine chemicals and drug metabolites manufactured by BioDynamics Research Ltd as Cypex branded products for drug metabolism studies.

1st June 2003
Cypex appoints M/S LabPro India as a distributor for the Indian market.

18th October 2002
Cypex acquires a non-exclusive licence from Brookhaven Science Associates LLC for commercial use of their T7 RNA polymerase technology.

23rd September 2002
Cypex appoints Nosan Corporation as a distributor for the Japanese market.

21st March 2002
PPD Discovery (Wilmington, N.C.) announces licence agreement with Cypex, giving Cypex a worldwide, non-exclusive licence to use PPD Discovery's proprietary Pharmazyme™ technology. PPD Discovery press release

22nd January 2002
Cypex appoints XenoTech as a distributor for the North American market.

6th December 2001
Cypex is upgraded to ISO9001:2000 Quality Standard.

1st October 2001
Cypex is appointed European distributor for Nosan Corporation's range of anti-human cytochrome P450 antibodies.

 

New products

8th August 2017
Pig CYP3A39BR Bactosomes (co-expressed recombinant pig CYP3A39 and pig NADPH-CYP reductase supplemented with human cytochrome b5) released for sale.

14th February 2017
New range of Bactosomes released, consisting of four pig CYPs, each co-expressed with pig NADPH-cytochrome P450 reductase.

12th April 2016
CYP17A1BR EasyCYP Bactosomes (co-expressed recombinant human CYP17A1 and human NADPH-CYP reductase supplemented with human cytochrome b5) released for sale.

15th January 2016
New products (human CYP17A1 and human CYP51) added to Cypex's range of purified recombinant enzymes. A full list is available here.

14th April 2015
Rat CYP3A2LR Bactosomes (co-expressed recombinant rat CYP3A2 and rat NADPH-CYP reductase) released for sale.

2nd April 2015
Rat CYP1A2LR Bactosomes and rat CYP2C11LR Bactosomes (both enzymes co-expressed with rat NADPH-CYP reductase) released for sale.

26th September 2014
The midazolam metabolites 1'-hydroxymidazolam and 4-hydroxymidazolam are released for sale.

8th August 2014
CYP46A1R Bactosomes and CYP46A1R EasyCYP Bactosomes (co-expressed recombinant human CYP46A1 and human NADPH-CYP reductase) released for sale.

6th August 2014
CYP46A1LR Bactosomes and CYP46A1LR EasyCYP Bactosomes (co-expressed recombinant human CYP46A1 and human NADPH-CYP reductase) released for sale.

24th February 2014
Rat CYP1B1LR Bactosomes (co-expressed recombinant rat CYP1B1 and rat NADPH-CYP reductase) released for sale.

13th January 2014
CYP17A1R Bactosomes and CYP17A1R EasyCYP Bactosomes (co-expressed recombinant human CYP17A1 and human NADPH-CYP reductase) released for sale.

5th November 2013
CYP17A1LR Bactosomes and CYP17A1LR EasyCYP Bactosomes (co-expressed recombinant human CYP17A1 and human NADPH-CYP reductase) released for sale.

18th October 2013
Dog CYP1B1LR Bactosomes (with dog CYP-reductase), rhesus monkey CYP1B1LR Bactosomes (with human CYP-reductase), and mouse CYP1B1LR Bactosomes (with mouse CYP-reductase) released for sale.

10th May 2013
The specification of human CES1 and CES2 is improved, resulting in products with significantly higher specific activity.

23rd April 2013
Anti-human CYP26B1 and anti-human CYP26C1 monoclonal antibodies are now available. The full list can be viewed here.

18th February 2013
Rat CYP2D18LR Bactosomes (co-expressed recombinant rat CYP2D18 and rat NADPH-cytochrome P450 reductase) released for sale.

11th February 2013
Rat CYP3A9LR Bactosomes (co-expressed recombinant rat CYP3A9 and rat NADPH-cytochrome P450 reductase) released for sale.

7th January 2013
CYP2C19BR Bactosomes and CYP2C19BR EasyCYP Bactosomes (co-expressed recombinant human CYP2C19 and human NADPH-CYP reductase supplemented with human cytochrome b5 ) released for sale.

12th December 2012
New range of Bactosomes announced, consisting of individual rat CYPs co-expressed with rat NADPH-cytochrome P450 reductase. The first product to be released is CYP2D4LR Bactosomes.

5th December 2012
CYP2A6BR Bactosomes and CYP2A6BR EasyCYP Bactosomes (co-expressed recombinant human CYP2A6 and human NADPH-CYP reductase supplemented with human cytochrome b5 ) released for sale.

9th November 2012
Vertebrate Antibodies' anti-CYP monoclonal antibodies can now be purchased from Cypex. The full list can be viewed here.

31st October 2012
CYP2C19BLR Bactosomes and CYP2C19BLR EasyCYP Bactosomes (co-expressed recombinant human CYP2C19 and human NADPH-CYP reductase supplemented with human cytochrome b5 ) released for sale.

16th July 2012
CYP2B6BLR Bactosomes and CYP2B6BLR EasyCYP Bactosomes (co-expressed recombinant human CYP2B6 and human NADPH-CYP reductase supplemented with human cytochrome b5 ) released for sale.

14th June 2012
Four more cynomolgus monkey CYPs are released for sale, extending the range to six enzymes. The new products, which consist of individual cynomolgus monkey CYPs co-expressed with human NADPH-CYP reductase are CYP2C19LR (CYP2C75) Bactosomes, CYP2C76LR Bactosomes, CYP3A4LR (CYP3A8) Bactosomes and CYP3A5LR Bactosomes .

13th June 2012
The specification of aldehyde oxidase is changed to give a higher total protein concentration and more enzyme per vial.

11th June 2012
New range of Bactosomes released, consisting of individual cynomolgus monkey CYPs co-expressed with human NADPH-cytochrome P450 reductase. The first two products to be released are CYP2C8LR (CYP2C20) Bactosomes and CYP2C9LR (CYP2C43) Bactosomes.

7th November 2011
CYP3A7BR EasyCYP Bactosomes (co-expressed recombinant human CYP3A7 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

5th September 2011
CYP3A7R EasyCYP Bactosomes (co-expressed recombinant human CYP3A7 and human NADPH-cytochrome P450 reductase) released for sale.

15th August 2011
CYP3A7BR Bactosomes and CYP3A7BLR Bactosomes (co-expressed recombinant human CYP3A7 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

28th June 2011
The CYP2C19/CYP2B6 substrate S-mephenytoin and the related CYP2C19 metabolite 4'-hydroxymephenytoin are released for sale.

3rd May 2011
CYP3A7R Bactosomes and CYP3A7LR Bactosomes (co-expressed recombinant human CYP3A7 and human NADPH-cytochrome P450 reductase) released for sale.

2nd May 2011
New range of Bactosomes released, consisting of individual mouse CYPs co-expressed with mouse NADPH-cytochrome P450 reductase. The first two products to be released are CYP2B10LR Bactosomes and CYP3A11LR Bactosomes.

1st April 2011
CYP4F3BR EasyCYP Bactosomes and CYP4F3BLR EasyCYP Bactosomes (co-expressed recombinant human CYP4F3B and human NADPH-cytochrome P450 reductase) released for sale.

1st April 2011
CYP4F3BBR EasyCYP Bactosomes and CYP4F3BBLR EasyCYP Bactosomes (co-expressed recombinant human CYP4F3B and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

24th February 2011
The CYP2C8 and CYP3A4 substrate diethoxyfluorescein (DEF) is released for sale.

4th February 2011
CYP4F3BBR Bactosomes and CYP4F3BBLR Bactosomes (co-expressed recombinant human CYP4F3B and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

28th January 2011
CYP1B1*4LR EasyCYP Bactosomes (co-expressed recombinant human CYP1B1.4 and human NADPH-cytochrome P450 reductase) released for sale.

19th January 2011
CYP4F3BR Bactosomes and CYP4F3BLR Bactosomes (co-expressed recombinant human CYP4F3B and human NADPH-cytochrome P450 reductase) released for sale.

19th January 2011
An improved version of UGT1A6 Bactosomes, with higher specific activity, is released for sale.

16th September 2010
CYP1B1*3LR EasyCYP Bactosomes (co-expressed recombinant human CYP1B1.3 and human NADPH-cytochrome P450 reductase) released for sale.

22nd July 2010
The CYP2C8 inhibitor montelukast is released for sale.

12th July 2010
CYP2B6LR EasyCYP Bactosomes (co-expressed recombinant human CYP2B6 and human NADPH-cytochrome P450 reductase) released for sale.

24th June 2010
CYP2A13R EasyCYP Bactosomes (co-expressed recombinant human CYP2A13 and human NADPH-cytochrome P450 reductase) released for sale.

21st May 2010
CYP2C8BR and CYP2C8BLR Bactosomes (co-expressed recombinant human CYP2C8 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

13th May 2010
CYP2C8BR EasyCYP Bactosomes and CYP2C8BLR EasyCYP Bactosomes (co-expressed recombinant human CYP2C8 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

21st April 2010
CYP2D6*39R EasyCYP Bactosomes (co-expressed recombinant human CYP2D6.39 and human NADPH-cytochrome P450 reductase) released for sale.

16th February 2010
CYP3A5BR Bactosomes and CYP3A5BR EasyCYP Bactosomes (co-expressed recombinant human CYP3A5 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

10th February 2010
CYP2C8LR Bactosomes (co-expressed recombinant human CYP2C8 and human NADPH-cytochrome P450 reductase) released for sale.

21st January 2010
CYP1A1LR EasyCYP Bactosomes and CYP2C8LR EasyCYP Bactosomes released for sale.

6th January 2010
CYP3A5R Bactosomes and CYP3A5R EasyCYP Bactosomes (co-expressed recombinant human CYP3A5 and human NADPH-cytochrome P450 reductase) released for sale.

30th November 2009
Human SULT1C4 released for sale.

30th September 2009
CYP3A5BLR EasyCYP Bactosomes (co-expressed recombinant human CYP3A5 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

21st September 2009
CYP3A5BLR Bactosomes (co-expressed recombinant human CYP3A5 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

2nd September 2009
Recombinant human aldehyde dehydrogenase ALDH1A1 released for sale.

19th June 2009
Human SULT1C2 released for sale.

21st April 2009
Human SULT1E1 released for sale.

17th April 2009
Recombinant human carboxylesterase 2 released for sale.

16th April 2009
CYP2C9*3BR Bactosomes and CYP2C9*3BR EasyCYP Bactosomes (co-expressed recombinant human CYP2C9.3 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

8th April 2009
CYP4A11BR Bactosomes and CYP4A11BR EasyCYP Bactosomes (co-expressed recombinant human CYP4A11 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

26th March 2009
Human SULT2A1 released for sale.

17th March 2009
Human SULT1A2 released for sale.

27th February 2009
Human SULT1A1*2 released for sale.

28th January 2009
Dog CYP panel further extended with the release of dog CYP1A2LR Bactosomes for sale.

2nd December 2008
CYP4F2BLR EasyCYP Bactosomes (co-expressed recombinant human CYP4F2 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

27th November 2008
Recombinant human carboxylesterase 1 released for sale.

29th October 2008
CYP2C9*2BR Bactosomes and CYP2C9*2BR EasyCYP Bactosomes (co-expressed recombinant human CYP2C9.2 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

28th October 2008
CYP2B6BR Bactosomes and CYP2B6BR EasyCYP Bactosomes (co-expressed recombinant human CYP2B6 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

21st October 2008
New range of Bactosomes released, consisting of seven dog CYPs, each co-expressed with dog NADPH-cytochrome P450 reductase.

3rd October 2008
CYP4F2BLR Bactosomes (co-expressed recombinant human CYP4F2 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

5th August 2008
CYP2A13LR EasyCYP Bactosomes (co-expressed recombinant human CYP2A13 and human NADPH-cytochrome P450 reductase) released for sale.

8th May 2008
CYP2C9*2R EasyCYP Bactosomes (co-expressed recombinant human CYP2C9.2 and human NADPH-cytochrome P450 reductase) released for sale.

23rd April 2008
CYP2C9*3R EasyCYP Bactosomes (co-expressed recombinant human CYP2C9.3 and human NADPH-cytochrome P450 reductase) released for sale.

16th April 2008
Recombinant human aldehyde oxidase released for sale.

24th March 2008
CYP2C9*3R Bactosomes (co-expressed recombinant human CYP2C9.3 and human NADPH-cytochrome P450 reductase) released for sale.

16th January 2008
CYP2E1BR Bactosomes and CYP2E1BR EasyCYP Bactosomes (co-expressed recombinant human CYP2E1 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

18th December 2007
CYP2C9BHR Bactosomes, CYP2C9BHR EasyCYP Bactosomes, CYP2C9BR Bactosomes and CYP2C9BR EasyCYP Bactosomes (co-expressed recombinant human CYP2C9 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

5th December 2007
The CYP2C8 metabolite desethylamodiaquine is released for sale.

12th November 2007
The CYP2C8 substrate amodiaquine is released for sale.

13th September 2007
CYP3A4BLR Bactosomes and CYP3A4BLR EasyCYP Bactosomes (co-expressed recombinant human CYP3A4 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

7th September 2007
CYP3A4BR Bactosomes and CYP3A4BR EasyCYP Bactosomes (co-expressed recombinant human CYP3A4 and human NADPH-cytochrome P450 reductase supplemented with human cytochrome b5) released for sale.

1st August 2007
The CYP3A4 and CYP2J2 substrate terfenadine is released for sale.

18th July 2007
The specific CYP2C19 inhibitor (-)-N-3-benzylphenobarbital is released for sale.

20th February 2007
EasyCYP range further extended with the release of CYP4A11LR EasyCYP Bactosomes for sale.

4th October 2006
EasyCYP range further extended with the release of CYP1B1LR, CYP2C18LR, CYP2D6*2R, CYP2D6*10R and CYP2J2LR EasyCYP Bactosomes for sale.

18th August 2006
CYP2J2LR Bactosomes (co-expressed recombinant human CYP2J2 and human NADPH-cytochrome P450 reductase) released for sale.

4th August 2006
CYP2A13R Bactosomes (co-expressed recombinant human CYP2A13 and human NADPH-cytochrome P450 reductase) released for sale.

3rd August 2006
EasyCYP range further extended with the release of CYP1A1R, CYP3A5LR and CYP4A11R EasyCYP Bactosomes for sale.

10th July 2006
EasyCYP range further extended with the release of CYP1A2LR, CYP2C9R, CYP2C19LR, CYP2D6LR and CYP3A4LR EasyCYP Bactosomes for sale.

8th June 2006
Larger pack size (5 mg) of 6alpha-hydroxypaclitaxel released for sale.

2nd June 2006
CYP2A13LR Bactosomes (co-expressed recombinant human CYP2A13 and human NADPH-cytochrome P450 reductase) released for sale.

30th May 2006
Diclofenac released for sale.

23rd May 2006
EasyCYP range extended with the release of CYP2A6R, CYP2B6R and CYP2E1R EasyCYP Bactosomes for sale.

6th April 2006
CYP2C9*2R Bactosomes (co-expressed recombinant human CYP2C9.2 and human NADPH-cytochrome P450 reductase) released for sale.

28th March 2006
Ketoconazole released for sale.

17th March 2006
Paclitaxel released for sale.

5th December 2005
Tienilic acid released for sale.

21st October 2005
CYP2D6*39R Bactosomes (co-expressed recombinant human CYP2D6.39 and human NADPH-cytochrome P450 reductase) released for sale.

18th October 2005
Human SULT1B1 released for sale.

3rd October 2005
CYP2D6*10R Bactosomes (co-expressed recombinant human CYP2D6.10 and human NADPH-cytochrome P450 reductase) released for sale.

16th August 2005
3-O-methylfluorescein released for sale.

21st June 2005
Omeprazole released for sale.

19th May 2005
EasyCYP range extended with the release of CYP2C8R EasyCYP Bactosomes for sale.

15th April 2005
First five CYPs in the new convenient EasyCYP format released for sale.

 

Visit our stand at the following meetings:

14th European ISSX Meeting
Cologne, Germany
June 26 - 29, 2017
Booth #507

21st North American ISSX Meeting
Providence, RI
September 24 - 28, 2017
Booth #325

Contact Cypex for more information.

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