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 Product Information Sheets:
 

Data sheets for all batches of Cypex products can be accessed from this page by following the appropriate link below:

Bactosomes (human cytochrome P450s)
Bactosomes (dog cytochrome P450s)
Bactosomes (mouse cytochrome P450s)
Bactosomes (monkey cytochrome P450s)
Bactosomes (pig cytochrome P450s)
Bactosomes (rat cytochrome P450s)
EasyCYP Bactosomes (human cytochrome P450s)
Other drug-metabolising enzymes
Control preparations
Chemicals
Antibodies

 

Data Sheets for Bactosomes (human CYPs):

CYP1A1:    CYP1A1R   CYP1A1LR

CYP1A2:    CYP1A2R   CYP1A2LR

CYP1B1:     CYP1B1LR   CYP1B1*3LR   CYP1B1*4LR

CYP2A6:     CYP2A6R

CYP2A6/b5:   CYP2A6BR

CYP2A13:   CYP2A13R   CYP2A13LR

CYP2B6:     CYP2B6R   CYP2B6LR

CYP2B6/b5:   CYP2B6BR   CYP2B6BLR

CYP2C8:     CYP2C8R   CYP2C8LR

CYP2C8/b5:   CYP2C8BR   CYP2C8BLR

CYP2C9.1:    CYP2C9HR   CYP2C9R

CYP2C9.1/b5:  CYP2C9BHR    CYP2C9BR

CYP2C9.2:    CYP2C9*2R

CYP2C9.2/b5:   CYP2C9*2BR

CYP2C9.3:    CYP2C9*3R

CYP2C9.3/b5:   CYP2C9*3BR

CYP2C18:   CYP2C18LR

CYP2C19:   CYP2C19R   CYP2C19LR

CYP2C19/b5:  CYP2C19BR    CYP2C19BLR

CYP2D6.1:    CYP2D6R   CYP2D6LR

CYP2D6.2:    CYP2D6*2R

CYP2D6.10:    CYP2D6*10R

CYP2D6.39:    CYP2D6*39R

CYP2E1:    CYP2E1R

CYP2E1/b5:    CYP2E1BR

CYP2J2:    CYP2J2LR

CYP3A4:     CYP3A4R   CYP3A4LR

CYP3A4/b5:  CYP3A4BR    CYP3A4BLR

CYP3A5:    CYP3A5R    CYP3A5LR

CYP3A5/b5:   CYP3A5BR    CYP3A5BLR

CYP3A7:    CYP3A7R    CYP3A7LR

CYP3A7/b5:   CYP3A7BR    CYP3A7BLR

CYP4A11:   CYP4A11R   CYP4A11LR

CYP4A11/b5:   CYP4A11BR

CYP4F2/b5:   CYP4F2BLR

CYP4F3B:   CYP4F3BR   CYP4F3BLR

CYP4F3B/b5:   CYP4F3BBR   CYP4F3BBLR

CYP17A1:   CYP17A1R   CYP17A1LR

CYP46A1:   CYP46A1R    CYP46A1LR

 

 

Data Sheets for Bactosomes (beagle dog CYPs):

CYP1A1:     CYP1A1LR

CYP1A2:     CYP1A2LR

CYP1B1:     CYP1B1LR

CYP2B11:    CYP2B11LR

CYP2C21:    CYP2C21LR

CYP2C41:    CYP2C41LR

CYP2D15:    CYP2D15LR

CYP3A12:    CYP3A12LR

CYP3A26:    CYP3A26LR

 

 

Data Sheets for Bactosomes (mouse CYPs):

Cyp1b1:    CYP1B1LR

Cyp2b10:    CYP2B10LR

Cyp3a11:    CYP3A11LR

 

 

Data Sheets for Bactosomes (monkey CYPs):

CYP1B1:                 CYP1B1LR (rhesus)

CYP2C8 (CYP2C20):    CYP2C8LR (cynomolgus)

CYP2C9 (CYP2C43):    CYP2C9LR (cynomolgus)

CYP2C19 (CYP2C75):   CYP2C19LR (cynomolgus)

CYP2C76:                CYP2C76LR (cynomolgus)

CYP3A4 (CYP3A8):    CYP3A4LR (cynomolgus)

CYP3A5:                 CYP3A5LR (cynomolgus)

 

 

Data Sheets for Bactosomes (pig CYPs):

CYP1A2:     CYP1A2LR

CYP2C49:     CYP2C49LR

CYP2E1:     CYP2E1BR

CYP3A39:     CYP3A39LR

 

 

Data Sheets for Bactosomes (rat CYPs):

CYP1A2:     CYP1A2LR

CYP1B1:     CYP1B1LR

CYP2C11:     CYP2C11LR

CYP2D4:     CYP2D4LR

CYP2D18:    CYP2D18LR

CYP3A2:     CYP3A2LR

CYP3A9:     CYP3A9LR

 

 

Data Sheets for EasyCYP Bactosomes (human CYPs):

CYP1A1:    CYP1A1R EasyCYP    CYP1A1LR EasyCYP

CYP1A2:    CYP1A2R EasyCYP   CYP1A2LR EasyCYP

CYP1B1.1:    CYP1B1LR EasyCYP

CYP1B1.3:    CYP1B1*3LR EasyCYP

CYP1B1.4:    CYP1B1*4LR EasyCYP

CYP2A6:    CYP2A6R EasyCYP

CYP2A6/b5:    CYP2A6BR EasyCYP

CYP2A13:   CYP2A13R EasyCYP    CYP2A13LR EasyCYP

CYP2B6:    CYP2B6R EasyCYP    CYP2B6LR EasyCYP

CYP2B6/b5:    CYP2B6BR EasyCYP    CYP2B6BLR EasyCYP

CYP2C8:    CYP2C8R EasyCYP    CYP2C8LR EasyCYP

CYP2C8/b5:    CYP2C8BR EasyCYP    CYP2C8BLR EasyCYP

CYP2C9.1:    CYP2C9HR EasyCYP   CYP2C9R EasyCYP

CYP2C9.1/b5:  CYP2C9BHR EasyCYP   CYP2C9BR EasyCYP

CYP2C9.2:    CYP2C9*2R EasyCYP

CYP2C9.2/b5:    CYP2C9*2BR EasyCYP

CYP2C9.3:    CYP2C9*3R EasyCYP

CYP2C9.3/b5:    CYP2C9*3BR EasyCYP

CYP2C18:    CYP2C18LR EasyCYP

CYP2C19:   CYP2C19R EasyCYP   CYP2C19LR EasyCYP

CYP2C19/b5:   CYP2C19BR EasyCYP   CYP2C19BLR EasyCYP

CYP2D6.1:    CYP2D6R EasyCYP   CYP2D6LR EasyCYP

CYP2D6.2:    CYP2D6*2R EasyCYP

CYP2D6.10:    CYP2D6*10R EasyCYP

CYP2D6.39:    CYP2D6*39R EasyCYP

CYP2E1:    CYP2E1R EasyCYP

CYP2E1/b5:    CYP2E1BR EasyCYP

CYP2J2:    CYP2J2LR EasyCYP

CYP3A4:    CYP3A4R EasyCYP   CYP3A4LR EasyCYP

CYP3A4/b5:  CYP3A4BR EasyCYP   CYP3A4BLR EasyCYP

CYP3A5:    CYP3A5R EasyCYP    CYP3A5LR EasyCYP

CYP3A5/b5:  CYP3A5BR EasyCYP   CYP3A5BLR EasyCYP

CYP3A7:    CYP3A7R EasyCYP

CYP3A7/b5:  CYP3A7BR EasyCYP

CYP4A11:   CYP4A11R EasyCYP   CYP4A11LR EasyCYP

CYP4A11/b5:   CYP4A11BR EasyCYP

CYP4F2/b5:   CYP4F2BLR EasyCYP

CYP4F3B:   CYP4F3BR EasyCYP   CYP4F3BLR EasyCYP

CYP4F3B/b5:   CYP4F3BBR EasyCYP   CYP4F3BBLR EasyCYP

CYP17A1:   CYP17A1R EasyCYP   CYP17A1LR EasyCYP

CYP17A1/b5:   CYP17A1BR EasyCYP

CYP46A1:   CYP46A1R EasyCYP    CYP46A1LR EasyCYP

 

 

Data sheets for other drug-metabolising enzymes:

Sulfotransferases:  SULT1A1*1  SULT1A1*2  SULT1A2   SULT1A3
       SULT1B1  SULT1C2   SULT1C4   SULT1E1   SULT2A1

Glutathione S-transferases:    GSTA1    GSTM1

Aldehyde oxidase

Aldehyde dehydrogenases:   ALDH1A1

Carboxylesterases:   CES1   CES2

UDP-glucuronosyltransferases:   UGT1A6

 

 

Data sheets for Control preparations:

Control Bactosomes

Control EasyCYP Bactosomes

Reductase Bactosomes

Control cytosol

 

 

Data sheets for chemicals:

Amodiaquine HCl

(-)-N-3-benzylphenobarbital

7-benzyloxyquinoline (7BQ)

7-benzyloxy-4-(trifluoromethyl)-coumarin (BFC)

Carboxytolbutamide

Carboxytolbutamide methyl ester

Desethylamodiaquine

Diclofenac sodium

Diethoxyfluorescein (DEF)

[3-14C] 7-ethoxycoumarin

7-ethoxyresorufin

7-hydroxy-4-aminomethyl-coumarin (HAMC)

4'-hydroxydiclofenac

[1-14C] 11-hydroxylauric acid

[1-14C] 12-hydroxylauric acid

()-4'-hydroxymephenytoin

1'-hydroxymidazolam

4-hydroxymidazolam

6a-hydroxypaclitaxel

7-hydroxyquinoline (7HQ)

Hydroxytolbutamide

7-hydroxy-4-(trifluoromethyl)-coumarin (HFC)

Ketoconazole

[1-14C] lauric acid

S-mephenytoin

7-methoxy-4-aminomethyl-coumarin (MAMC)

7-methoxy-4-(trifluoromethyl)-coumarin (MFC)

3-O-methylfluorescein

Montelukast sodium

Paclitaxel

Resorufin, sodium salt

Terfenadine

Tienilic acid

Tolbutamide

 

 

Data Sheets for antibodies:

Anti-rat liver UGT

Anti-human SULT1A3

Control serum


antibodies distributed by Cypex (Europe only):

Anti-human CYP1A1/2

Anti-human CYP1A2

Anti-human CYP2A6

Anti-human CYP2C8 (PAP 081 - inhibition and blotting)

Anti-human CYP2C8 (PAI 081 - inhibition only)

Anti-human CYP2C9 (PAP 091 - inhibition and blotting)

Anti-human CYP2C9 (PAI 091 - inhibition only)

Anti-human CYP2C19

Anti-human CYP2D6

Anti-human CYP2E1

Anti-human CYP3A4

Anti-rat CYP1A1

Anti-rat CYP2B1

Anti-rat CYP2C11

Anti-rat CYP3A2

Anti-rat CYP4A1

Control serum

 

 

VA logo

Monoclonal antibodies distributed by Cypex:

Anti-human CYP1A

Anti-human CYP1A2

Anti-human CYP1B1

Anti-human CYP2A (this antibody is not held in stock, but it can be ordered)

Anti-human CYP2A6

Anti-human CYP2E1

Anti-human CYP2R1

Anti-human CYP3A4

Anti-human CYP3A5

Anti-human CYP3A7

Anti-human CYP4A11

Anti-human CYP4F11

Anti-human CYP4V2

Anti-human CYP4Z1

Anti-human CYP7B1

Anti-human CYP8B1

Anti-human CYP26A1

Anti-human CYP26B1

Anti-human CYP26C1

Anti-human CYP39A1

Anti-human CYP51A1

 

Important: By purchasing these products from Cypex you accept the standard terms and conditions of supply.

The following are made under licence from BTG International Ltd (AU730155, EP0914446, US6566108 and other patents pending): all recombinant cytochrome P450 products; 4'-hydroxydiclofenac; 6alpha-hydroxypaclitaxel.

United States Patent Nos. 5,420,027 or 5,240,831, Canada Patent No. 2100245 and other patents pending.


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